With Juvéderm Ultra Plus, and Voluma, one treatment typically offers significant results. However, we may fine-tune your results with an additional visit. Each CoolMini treatment provides 25% fat reduction to the treated area, so your goals will determine number of visits. Kybella medicine is made of deoxycholic acid, a naturally occurring molecule in the body that aids in the breakdown of fat. This is a gradual process, and you should expect to need 2-6 Kybella treatments to achieve optimal results.